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Article

A new perspective on population genetics: Deciphering the relationship between genetic variants and disease prevalence in Psoriasis.

PloS one - 1 Jan 2026

Zhang Yuanjing, Li Weiran, Wang Wanrong, Wu Kejia, Zhou Feiran, Zheng Xiaodong

Abstract excerpt

In the quest to identify the genetic underpinnings of complex diseases, we developed a novel approach called Causal Genotype Combination Patterns (CGCP) to uncover characteristic genetic signatures of common diseases. In this study, we applied the CGCP method to a whole-exome sequencing dataset of 781 psoriasis cases and 676 healthy controls from the Chinese Han population. Our analysis revealed 620 genotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41824440
DOI: 10.1371/journal.pone.0344204
PMCID: PMC12987435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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