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Article

Association study of NFKB1 and SUMO4 polymorphisms in Chinese patients with psoriasis vulgaris.

Archives of dermatological research - 1 Sept 2008

Li Hong, Gao Lin, Shen Zhu, Li Chun Ying, Li Kai, Li Miao, Lv Ya Jie, Li Cheng Xin, Gao Tian Wen, Liu Yu Feng

Abstract excerpt

Nuclear factor kappa-beta (NF-kappaB) is a critical transcription factor modulating the expression of many genes involved in the pathogenesis of psoriasis. SUMO4 is a negative regulator of NF-kappaB in the cell-signaling pathway. Two functional polymorphisms of the NFKB1 and SUMO4 genes have been found to be associated with the risks of some autoimmune-related diseases, but no published study has investigated the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18330586
DOI: 10.1007/s00403-008-0843-4

Genes

NFKB1
SUMO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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