Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders.

doi:10.1002/ajmg.b.32467

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Article

Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2017

Lester Kathryn J, Coleman Jonathan R I, Roberts Susanna, Keers Robert, Breen Gerome, Bögels Susan, Creswell Cathy, Hudson Jennifer L, McKinnon Anna, Nauta Maaike, Rapee Ronald M, Schneider Silvia, Silverman Wendy K, Thastum Mikael, Waite Polly, Wergeland Gro Janne H, Eley Thalia C

Abstract excerpt

Extinction learning is an important mechanism in the successful psychological treatment of anxiety. Individual differences in response and relapse following Cognitive Behavior Therapy may in part be explained by variability in the ease with which fears are extinguished or the vulnerability of these fears to re-emerge. Given the role of the endocannabinoid system in fear extinction, this study investigates whether...

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Identifiers

PMID: 27346075
DOI: 10.1002/ajmg.b.32467
PMCID: PMC5324578

Genes

CNR1
CNR2
FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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