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Article

DNA Damage Is a Potential Marker for TP53 Mutation in Colorectal Carcinogenesis.

Journal of gastrointestinal cancer - 1 Dec 2016

Scalise José Ricardo, Poças Regina Caeli Guerra, Caneloi Thamy Pelatieri, Lopes Camila Oliveira, Kanno Danilo Toshio, Marques Mayara Gonçalves, Valdivia Júlio Cesar Martins, Maximo Felipe Rodrigues, Pereira José Aires, Ribeiro Marcelo Lima, Priolli Denise Gonçalves

Abstract excerpt

PURPOSE: The ability to measure oxidative DNA damage in a tissue allows establishment of the relationship between DNA damage and mutations in normal and neoplastic cells. It is well known that TP53 is a key inhibitor of tumor development and preserves the genome integrity in each cell. The aim of the present study was to investigate the relationship between DNA damage and TP53 mutation in colorectal adenoma and...

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Identifiers

PMID: 27342962
DOI: 10.1007/s12029-016-9846-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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