Article
The effects of oxidative DNA damage and mutations in the p53 protein on cells of the colonic mucosa with and without the fecal stream: an experimental study in rats.
Scandinavian journal of gastroenterology - 1 Jun 2010
Martinez Carlos Augusto Real, Bartocci Priscila Cecília Mendes, do Carmo Carlos Vieira, Pereira José Aires, Miranda Daniel Duarte da Conceição, Ribeiro Marcelo Lima
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the levels of oxidative DNA damage and p53 mutations in an experimental model of diversion colitis. MATERIAL AND METHODS: Sixty rats were divided into three groups with 20 animals in accordance with the sacrifice was carried out 6, 12 and 18 wee...
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