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Article

Genetic characteristics of mitochondrial DNA was associated with colorectal carcinogenesis and its prognosis.

PloS one - 1 Jan 2015

Lee Jae-Ho, Hwang Ilseon, Kang Yu-Na, Choi In-Jang, Kim Dae-Kwang

Abstract excerpt

Clinical value of mitochondrial DNA has been described in colorectal cancer (CRC). To clarify its role in colorectal carcinogenesis, mitochondrial microsatellite instability (mtMSI) and other markers were investigated in CRCs and their precancerous lesions, as a multitier genetic study. DNA was isolated from paired normal and tumoral tissues in 78 tubular adenomas (TAs), 34 serrated polyps (SPs), and 100 CRCs....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25734426
DOI: 10.1371/journal.pone.0118612
PMCID: PMC4348484

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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