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Clinicopathological significance of EGFR pathway gene mutations and CRTC1/3-MAML2 fusions in salivary gland mucoepidermoid carcinoma.

Histopathology - 1 Jun 2020

Morita Maki, Murase Takayuki, Okumura Yoshihide, Ueda Kaori, Sakamoto Yuma, Masaki Ayako, Kawakita Daisuke, Tada Yuichiro, Nibu Ken-Ichi, Shibuya Yasuyuki, Inagaki Hiroshi

Abstract excerpt

AIMS: Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland carcinomas. Epidermal growth factor receptor (EGFR) signalling pathway gene mutations are important in predicting a patient's prognosis, selecting molecularly targeted drugs and estimating the efficacy of a molecular therapy. However, their significance in MEC have been poorly clarified. CRTC1/3-MAML2 fusions are specific to MEC and may...

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PMID: 32129900
DOI: 10.1111/his.14100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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