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Article

Splicing mutation in Sbf1 causes nonsyndromic male infertility in the rat.

Reproduction (Cambridge, England) - 1 Sept 2016

Liška František, Chylíková Blanka, Janků Michaela, Šeda Ondřej, Vernerová Zdeňka, Pravenec Michal, Křen Vladimír

Abstract excerpt

In the inbred SHR/OlaIpcv rat colony, we identified males with small testicles and inability to reproduce. By selectively breeding their parents, we revealed the infertility to segregate as an autosomal recessive Mendelian character. No other phenotype was observed in males, and females were completely normal. By linkage using a backcross with Brown Norway strain, we mapped the locus to a 1.2Mbp segment on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27335132
DOI: 10.1530/REP-16-0042

Genes

SBF1
MTMR2
SET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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