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Article

Identification of potentially damaging amino acid substitutions leading to human male infertility.

Biology of reproduction - 1 Aug 2009

Kuzmin Anastasia, Jarvi Keith, Lo Kirk, Spencer Leia, Chow Gary Y C, Macleod Graham, Wang Qianwei, Varmuza Susannah

Abstract excerpt

There are a number of known genetic alterations found in men with nonobstructive azoospermia, or testicular failure, such as Y microdeletions and cytogenetic abnormalities. However, the etiology of nonobstructive azoospermia is unknown in the majority of men. The aim of this study was to investigate the possibility that unexplained cases of nonobstructive azoospermia are caused by nonsynonymous single-nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19369647
DOI: 10.1095/biolreprod.109.076000
PMCID: PMC2849822

Genes

LIMK2
LIPE
SBF1
TBPL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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