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Article

Identification of a New QTL Region on Mouse Chromosome 1 Responsible for Male Hypofertility: Phenotype Characterization and Candidate Genes.

International journal of molecular sciences - 12 Nov 2020

Vatin Magalie, Girault Marie-Sophie, Firlej Virginie, Marchiol Carmen, Ialy-Radio Côme, Montagutelli Xavier, Vaiman Daniel, Barbaux Sandrine, Ziyyat Ahmed

Abstract excerpt

Male fertility disorders often have their origin in disturbed spermatogenesis, which can be induced by genetic factors. In this study, we used interspecific recombinant congenic mouse strains (IRCS) to identify genes responsible for male infertility. Using ultrasonography, in vivo and in vitro fertilization (IVF) and electron microscopy, the phenotyping of several IRCS carrying mouse chromosome 1 segments of Mus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33198087
DOI: 10.3390/ijms21228506
PMCID: PMC7697627

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