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Article

Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice.

Molecular and cellular biology - 1 Feb 2007

Kress Chantal, Gautier-Courteille Carole, Osborne H Beverley, Babinet Charles, Paillard Luc

Abstract excerpt

CUG-BP1/CELF1 is a multifunctional RNA-binding protein involved in the regulation of alternative splicing and translation. To elucidate its role in mammalian development, we produced mice in which the Cugbp1 gene was inactivated by homologous recombination. These Cugbp1(-/-) mice were viable, alt...

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Identifiers

PMID: 17130239
DOI: 10.1128/MCB.01009-06
PMCID: PMC1800704

Genes

CELF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17130239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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