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Article

Elimination of a ligand gating site generates a supersensitive olfactory receptor.

Scientific reports - 21 Jun 2016

Sharma Kanika, Ahuja Gaurav, Hussain Ashiq, Balfanz Sabine, Baumann Arnd, Korsching Sigrun I

Abstract excerpt

Olfaction poses one of the most complex ligand-receptor matching problems in biology due to the unparalleled multitude of odor molecules facing a large number of cognate olfactory receptors. We have recently deorphanized an olfactory receptor, TAAR13c, as a specific receptor for the death-associated odor cadaverine. Here we have modeled the cadaverine/TAAR13c interaction, exchanged predicted binding residues by...

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Identifiers

PMID: 27323929
DOI: 10.1038/srep28359
PMCID: PMC4914996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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