Article
Relationship between amino acid properties and functional parameters in olfactory receptors and discrimination of mutants with enhanced specificity.
BMC bioinformatics - 8 May 2012
Gromiha M Michael, Harini K, Sowdhamini R, Fukui Kazuhiko
Abstract excerpt
BACKGROUND: Olfactory receptors are key components in signal transduction. Mutations in olfactory receptors alter the odor response, which is a fundamental response of organisms to their immediate environment. Understanding the relationship between odorant response and mutations in olfactory receptors is an important problem in bioinformatics and computational biology. In this work, we have systematically...
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