Article
Forging our understanding of lncRNAs in the brain.
Cell and tissue research - 1 Jan 2018
Andersen Rebecca E, Lim Daniel A
Abstract excerpt
During both development and adulthood, the human brain expresses many thousands of long noncoding RNAs (lncRNAs), and aberrant lncRNA expression has been associated with a wide range of neurological diseases. Although the biological significance of most lncRNAs remains to be discovered, it is now clear that certain lncRNAs carry out important functions in neurodevelopment, neural cell function, and perhaps even...
Topics
- Alleles
- Animals
- Brain
- Brain Diseases
- Gene Expression Regulation
- Humans
- Interneurons
- Mice
- Mice, Transgenic
- Models, Animal
- Mutation
- Neurons
- RNA, Long Noncoding