Article
Impaired fasting glucose is associated with increased regional cerebral amyloid.
Neurobiology of aging - 1 Aug 2016
Morris Jill K, Vidoni Eric D, Wilkins Heather M, Archer Ashley E, Burns Nicole C, Karcher Rainer T, Graves Rasinio S, Swerdlow Russell H, Thyfault John P, Burns Jeffrey M
Abstract excerpt
The Alzheimer's disease risk gene apolipoprotein E epsilon 4 (APOE ε4) is associated with increased cerebral amyloid. Although impaired glucose metabolism is linked to Alzheimer's disease risk, the relationship between impaired glycemia and cerebral amyloid is unclear. To investigate the independent effects of APOE ε4 and impaired glycemia on cerebral amyloid, we stratified nondemented subjects (n = 73) into 4...
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