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Article

Beta-amyloid associated differential effects of APOE ε4 on brain metabolism in cognitively normal elderly.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Oct 2014

Yi Dahyun, Lee Dong Y, Sohn Bo K, Choe Young M, Seo Eun H, Byun Min S, Woo Jong I

Abstract excerpt

OBJECTIVE: Although apolipoprotein (APOE) ε4 allele is a well-established risk factor for late-onset Alzheimer disease (AD), the mechanism of its effects on AD pathogenesis is not fully understood. We aimed to investigate the effects of APOE genotype on regional cerebral glucose metabolism in cog...

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Source

Identifiers

PMID: 24495404
DOI: 10.1016/j.jagp.2013.12.173

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24495404-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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