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Article

Diabetes mellitus contributes to higher cerebrospinal fluid tau levels selectively in Alzheimer's disease patients with the APOE4 genotype.

European journal of neurology - 1 Dec 2021

Motta Caterina, Assogna Martina, Bonomi Chiara Giuseppina, Mascolo Alfredo Paolo, De Lucia Vincenzo, Semprini Roberta, Mercuri Nicola Biagio, Koch Giacomo, Martorana Alessandro

Abstract excerpt

BACKGROUND AND PURPOSE: Diabetes mellitus (DM) is considered a risk factor for Alzheimer's disease (AD) and shares some pathological pathways, such as activation of amyloid cascade and tau phosphorylation. The aim of the present study was to investigate to what extent DM could impact on neurodegeneration within the AD continuum, using β amyloid (A: Aβ1-42 ) and phosphorylated tau (T: p-tau) biomarkers to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34309155
DOI: 10.1111/ene.15039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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