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Article

Genotype-phenotype correlation of age-related macular degeneration: influence of complement factor H polymorphism.

The British journal of ophthalmology - 1 Apr 2008

Droz I, Mantel I, Ambresin A, Faouzi M, Schorderet D F, Munier F L

Abstract excerpt

BACKGROUND/AIMS: Complement factor H (CFH) Y402H polymorphism shows a strong association with age-related macular degeneration (AMD). Although the phenotypic concordance of AMD has been shown in sibling/twin studies, little is known about the genotype-phenotype association. In this study, we investigated whether CFH Y402H is associated with early phenotypic features. METHODS: Statistical analysis was performed on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18211923
DOI: 10.1136/bjo.2007.127811

Genes

CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genotype-phenotype correlation of age-related macular degeneration: influence of complement factor H polymorphism.PMID 18211923Read ↗

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