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Article

C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes.

PloS one - 21 May 2008

Jakobsdottir Johanna, Conley Yvette P, Weeks Daniel E, Ferrell Robert E, Gorin Michael B

Abstract excerpt

BACKGROUND: Age-related maculopathy (ARM) is a common cause of visual impairment in the elderly populations of industrialized countries and significantly affects the quality of life of those suffering from the disease. Variants within two genes, the complement factor H (CFH) and the poorly characterized LOC387715 (ARMS2), are widely recognized as ARM risk factors. CFH is important in regulation of the alternative...

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Source

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Identifiers

PMID: 18493315
DOI: 10.1371/journal.pone.0002199
PMCID: PMC2374901

Genes

CFH
CFB
ARMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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