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Article

Polymorphisms in selected DNA repair genes and cell cycle regulating genes involved in the risk of papillary thyroid carcinoma.

Cancer biomarkers : section A of Disease markers - 7 Jun 2016

Halkova Tereza, Dvorakova Sarka, Sykorova Vlasta, Vaclavikova Eliska, Vcelak Josef, Vlcek Petr, Sykorova Pavla, Kodetova Daniela, Betka Jan, Lastuvka Petr, Bavor Petr, Hoch Jiri, Katra Rami, Bendlova Bela

Abstract excerpt

BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. In addition to causal somatic mutations in the BRAF gene and RET/PTC rearrangements, the contribution of single nucleotide polymorphisms (SNPs) in low-penetrance genes in the development of PTC has been proposed. METHODS: Four SNPs in the XRCC1 (Arg399Gln, Arg280His, Arg194Trp and T-77C) and one SNP from each of three other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27314298
DOI: 10.3233/CBM-160622
PMCID: PMC13020473

Genes

XRCC1
ATM
CDKN1B
RET
TP53
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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