Article
Interaction among susceptibility genotypes of PARP1 SNPs in thyroid carcinoma.
PloS one - 1 Jan 2018
Bashir Kashif, Sarwar Romana, Saeed Soma, Mahjabeen Ishrat, Kayani Mahmood Akhtar
Abstract excerpt
Polymorphisms in DNA repair genes may alter the repair mechanism which makes the person susceptible to DNA damage. Polymorphic variants in these DNA repair pathway genes such as Poly (ADP-ribose) polymerase- 1 (PARP1) have been associated with susceptibility of several types of cancer including thyroid. Many studies have been published on PARP1 gene polymorphisms and carcinogenesis with inconsistent results. The...
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