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Article

Polymorphisms in base excision repair genes and thyroid cancer risk.

Oncology reports - 1 Nov 2012

Santos Luís S, Branco Sandra C, Silva Susana N, Azevedo Ana Paula, Gil Octávia M, Manita Isabel, Ferreira Teresa C, Limbert Edward, Rueff José, Gaspar Jorge F

Abstract excerpt

Thyroid cancer (TC) is the most frequent endocrine malignancy, accounting however for only 1-2% of all human cancers, and the best-established risk factor for TC is radiation exposure, particularly during childhood. Since the BER pathway seems to play an important role in the repair of DNA damage induced by IR and other genotoxicants, we carried out a hospital-based case-control study in order to evaluate the...

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Source

Identifiers

PMID: 22922830
DOI: 10.3892/or.2012.1975

Genes

MUTYH
APEX1
OGG1
PARP1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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