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Article

A novel model of THO/TREX loading onto target RNAs in metazoan gene expression.

BMB reports - 1 Jul 2016

Hur Junho K, Chung Yun Doo

Abstract excerpt

The THO/TREX complex consists of several conserved subunits and is required for mRNA export. In metazoans, THO/TREX binds a subset of mRNAs during RNA splicing, and facilitates their nuclear export. How THO/TREX selects RNA targets is, however, incompletely understood. In our recent study, we reported that THO is loaded onto Piwi-interacting RNA (piRNA) precursor transcripts independent of splicing, and...

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Identifiers

PMID: 27312604
DOI: 10.5483/bmbrep.2016.49.7.099
PMCID: PMC5032001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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