Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients.

doi:10.1002/alr.21803

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Article

Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients.

International forum of allergy & rhinology - 1 Aug 2016

Adappa Nithin D, Truesdale Carl M, Workman Alan D, Doghramji Laurel, Mansfield Corrine, Kennedy David W, Palmer James N, Cowart Beverly J, Cohen Noam A

Abstract excerpt

BACKGROUND: Sinonasal biofilms have been demonstrated in specimens collected from chronic rhinosinusitis (CRS) patients. Mounting evidence suggests that biofilms contribute to therapeutically recalcitrant CRS. Recently, the bitter taste receptor T2R38 has been implicated in the regulation of the sinonasal mucosal innate immune response. TAS2R38 gene polymorphisms affect receptor functionality and contribute to...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Biofilms
Chronic Disease
Female
Genotype
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenylthiourea

Pseudomonas

Receptors, G-Protein-Coupled

Rhinitis

Sinusitis

Taste

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 27309535
DOI: 10.1002/alr.21803
PMCID: PMC5500301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27309535-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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