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Article

Stalk cell differentiation without polyketides in the cellular slime mold.

Bioscience, biotechnology, and biochemistry - 1 Jul 2016

Sato Yukie G, Suarez Teresa, Saito Tamao

Abstract excerpt

Polyketides induce prestalk cell differentiation in Dictyostelium. In the double-knockout mutant of the SteelyA and B polyketide synthases, most of the pstA cells-the major part of the prestalk cells-are lost, and we show by whole mount in situ hybridization that expression of prestalk genes is also reduced. Treatment of the double-knockout mutant with the PKS inhibitor cerulenin gave a further reduction, but...

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Identifiers

PMID: 27305283
DOI: 10.1080/09168451.2016.1162087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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