Article
Protein kinase B gene homologue pkbR1 performs one of its roles at first finger stage of Dictyostelium.
Eukaryotic cell - 1 Apr 2011
Ochiai Hiroshi, Takeda Kosuke, Fukuzawa Masashi, Kato Atsushi, Takiya Shigeharu, Ohmachi Tetsuo
Abstract excerpt
Dictyostelium discoideum has protein kinases AKT/PKBA and PKBR1 that belong to the AGC family of kinases. The protein kinase B-related kinase (PKBR1) has been studied with emphasis on its role in chemotaxis, but its roles in late development remained obscure. The pkbR1 null mutant stays in the first finger stage for about 16 h or longer. Only a few aggregates continue to the migrating slug stage; however, the...
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