Article
TagA, a putative serine protease/ABC transporter of Dictyostelium that is required for cell fate determination at the onset of development.
Development (Cambridge, England) - 1 Jul 2003
Good J Randall, Cabral Matthew, Sharma Sujata, Yang Jun, Van Driessche Nancy, Shaw Chad A, Shaulsky Gad, Kuspa Adam
Abstract excerpt
The tag genes of Dictyostelium are predicted to encode multi-domain proteins consisting of serine protease and ATP-binding cassette transporter domains. We have identified a novel tag gene, tagA, which is involved in cell type differentiation. The tagA mRNA accumulates during the first four hours of development, whereas TagA protein accumulates between two and ten hours of development and decreases thereafter....
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