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Article

Association of ABCC Gene Polymorphism With Susceptibility to Antituberculosis Drug-Induced Hepatotoxicity in Western Han Patients With Tuberculosis.

Journal of clinical pharmacology - 1 Mar 2020

Bai Hao, Wu Tao, Jiao Lin, Wu Qian, Zhao Zhenzhen, Song Jiajia, Liu Tangyuheng, Lv Yanghua, Lu Xiaojun, Ying Binwu

Abstract excerpt

Six-month combination regimens could lead to serious hepatotoxicity, which may limit the clinical use of antituberculosis drugs. ABCC transporters are critical to the influx and efflux of compounds into and out of cells. The aim of this study was to explore whether the genetic variants in ABCC genes were related to the development of antituberculosis drug-induced hepatotoxicity. Here, we screened and genotyped 39...

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Identifiers

PMID: 31648372
DOI: 10.1002/jcph.1533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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