Article
Do genetic polymorphisms of B-cell CLL/lymphoma 2 confer susceptibility to anti-tuberculous therapy-associated drug-induced liver injury?
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Feb 2020
Lyu Mengyuan, Jiao Lin, Zhou Jian, Li Haijun, Meng Zirui, Xie Wanhong, Ren Jing, Bian Qin, Ying Binwu
Abstract excerpt
OBJECTIVES: The aim of this study was to identify the relationship between B-cell CLL/lymphoma 2 (BCL2) polymorphisms and susceptibility to anti-tuberculous therapy-associated drug-induced liver injury (ATT-DILI). METHODS: A total of 746 tuberculosis (TB) patients were enrolled in this study. Twenty-one selected single nucleotide polymorphisms in BCL2 were analyzed by custom-by-design 2×48-Plex SNPscan kit. The...
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