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Article

Imputing Phenotypes for Genome-wide Association Studies.

American journal of human genetics - 7 Jul 2016

Hormozdiari Farhad, Kang Eun Yong, Bilow Michael, Ben-David Eyal, Vulpe Chris, McLachlan Stela, Lusis Aldons J, Han Buhm, Eskin Eleazar

Abstract excerpt

Genome-wide association studies (GWASs) have been successful in detecting variants correlated with phenotypes of clinical interest. However, the power to detect these variants depends on the number of individuals whose phenotypes are collected, and for phenotypes that are difficult to collect, the sample size might be insufficient to achieve the desired statistical power. The phenotype of interest is often...

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Identifiers

PMID: 27292110
DOI: 10.1016/j.ajhg.2016.04.013
PMCID: PMC5005435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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