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Article

Integrating GWAS summary statistics, individual-level genotypic and omic data to enhance the performance for large-scale trait imputation.

Human molecular genetics - 26 Aug 2023

Ren Jingchen, Lin Zhaotong, Pan Wei

Abstract excerpt

Recently, a non-parametric method has been proposed to impute the genetic component of a trait for a large set of genotyped individuals based on a separate genome-wide association study (GWAS) summary dataset of the same trait (from the same population). The imputed trait may contain linear, non-linear and epistatic effects of genetic variants, thus can be used for downstream linear or non-linear association...

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PMID: 37369060
DOI: 10.1093/hmg/ddad097
PMCID: PMC10460491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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