Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The value of relatives with phenotypes but missing genotypes in association studies for quantitative traits.

Genetic epidemiology - 1 Jan 2006

Visscher Peter M, Duffy David L

Abstract excerpt

The additional statistical power of association studies for quantitative traits was derived when ungenotyped relatives with phenotypes are included in the analysis. It was shown that the extra power is a simple function of the coefficient of additive genetic relationship and the phenotypic correl...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genotype
Share to Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Regression Analysis

Share to Twins, Monozygotic

Source

Identifiers

PMID: 16355405
DOI: 10.1002/gepi.20124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16355405-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The value of relatives with phenotypes but missing genotypes in association studies for quantitative traits.PMID 16355405Read ↗

Genome-wide association mapping including phenotypes from relatives without genotypes.Semantic proximity Read ↗

Mendelian imputation of parental genotypes for genome-wide estimation of direct and indirect genetic effectsSemantic proximity Read ↗

Phenotypically Enriched Genotypic Imputation in Genetic Association Tests.Semantic proximity Read ↗

Mapping quantitative-trait loci in humans by use of extreme concordant sib pairs: selected sampling by parental phenotypes.Semantic proximity Read ↗

Rare variant association analysis in case-parents studies by allowing for missing parental genotypes.Semantic proximity Read ↗

Missing single nucleotide polymorphisms in Genetic Risk Scores: A simulation study.Semantic proximity Read ↗

Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairsSemantic proximity Read ↗

Imputing Phenotypes for Genome-wide Association Studies.Semantic proximity Read ↗

A method for identifying genes related to a quantitative trait, incorporating multiple siblings and missing parents.Semantic proximity Read ↗

Accounting for linkage in family-based tests of association with missing parental genotypes.Semantic proximity Read ↗

Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs.Semantic proximity Read ↗

Power calculations for likelihood ratio tests for offspring genotype risks, maternal effects, and parent-of-origin (POO) effects in the presence of missing parental genotypes when unaffected siblings are available.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.