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Article

Mutations in Melanocortin-3 Receptor Gene and Human Obesity.

Progress in molecular biology and translational science - 1 Jan 2016

Yang Z, Tao Y-X

Abstract excerpt

The prevalence of obesity calls for novel therapeutic targets. The melanocortin-3 receptor (MC3R) has been increasingly recognized as an important regulator of energy homeostasis and MC3R has been intensively analyzed in molecular genetic studies for obesity-related traits. Twenty-seven MC3R mutations and two common polymorphic variants have been identified so far in different cohorts. The mutant MC3Rs...

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PMID: 27288827
DOI: 10.1016/bs.pmbts.2016.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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