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Article

Melanocortin 3 receptor gene and melanocortin 4 receptor gene mutations: the Asian Perspective.

Diabetes/metabolism research and reviews - 1 Dec 2012

Lee Yung Seng

Abstract excerpt

Melanocortin 4 receptor (MC4R) deficiency resulting from disruption of one or both MC4R alleles represents the commonest monogenic form of human obesity to date. Human MC4R deficiency was reported to affect 4 and 5.8% of severely obese French and British populations respectively. However, studies elsewhere reported low incidence of MC4R mutations in their obese populations. The significance of MC4R mutations in...

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PMID: 23280863
DOI: 10.1002/dmrr.2351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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