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Article

Presence of cerebral amyloid modulates phenotype and pattern of neurodegeneration in early Parkinson's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2016

McMillan Corey T, Wolk David A

Abstract excerpt

OBJECTIVE: To evaluate the frequency of cerebral amyloid in early Parkinson's disease (ePD) and provide a multimodal assessment of the influence of cerebral amyloid on disease phenotype. METHODS: We performed a multicentre cohort study of the Parkinson's Progression Markers Initiative (PPMI), including 369 drug-naïve patients with ePD and 174 healthy controls (HC). Cerebrospinal fluid (CSF) amyloid-β levels were...

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Amyloidosis
Brain Diseases
Brain Mapping
Disability Evaluation
Image Interpretation, Computer-Assisted

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Imaging, Three-Dimensional

Neurodegenerative Diseases

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PMID: 27288043
DOI: 10.1136/jnnp-2015-312690
PMCID: PMC5154297

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APOE

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