Article

Structural heterogeneity reveals distinct amyloidopathies in Alzheimer’s disease

2025-11-19

Abstract excerpt

Within the amyloid/tau/neurodegeneration (ATN) framework, hippocampal (H) and inferior parietal lobule (IPL) atrophy are established markers of neurodegeneration (N+), whereas the biological significance of choroid plexus (ChP) enlargement remains uncertain. Although amyloid positivity (A+) underpins the current biological definition of Alzheimer’s disease, the extent to which it is consistently associated with st...

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Literature Corpus work: 78ab338e-06aa-5ca1-abaf-1479bf5371a5
DOI: 10.1101/2025.11.17.25340406

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