Article

Cognitive impairment in Parkinson's disease : impact and identification of comorbid disease mechanisms

2020-01-01

Abstract excerpt

Cognitive impairment is a common and debilitating feature of Parkinson's disease (PD). While it is primarily caused by cerebral propagation of α-synuclein protein, evidence of comorbid diseases is frequently found in autopsy samples. This includes tau and amyloid-β pathologies – the hallmarks of Alzheimer's disease (AD) – and cerebrovascular damage. Comorbid diseases may influence cognition in PD over and above th...

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Literature Corpus work: 1b2aa10c-bb2f-5b93-b608-2f35a72533ac
DOI: 10.5525/gla.thesis.77862

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