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Article

Cerebrospinal fluid amyloid-β and phenotypic heterogeneity in de novo Parkinson's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 May 2013

Alves Guido, Pedersen Kenn Freddy, Bloem Bastiaan R, Blennow Kaj, Zetterberg Henrik, Borm George F, Dalaker Turi O, Beyer Mona K, Aarsland Dag, Andreasson Ulf, Lange Johannes, Tysnes Ole-Bjørn, Zivadinov Robert, Larsen Jan Petter

Abstract excerpt

BACKGROUND: In Parkinson's disease (PD), the motor presentation characterised by postural instability/gait difficulties (PIGD) heralds accelerated motor, functional and cognitive decline, as compared with the more benign tremor-dominant (TD) variant. This makes the PIGD complex an attractive target for the discovery of prognostic biomarkers in PD. OBJECTIVE: To explore in vivo whether variability in brain...

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Identifiers

PMID: 23117496
DOI: 10.1136/jnnp-2012-303808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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