Article
CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson's disease: the Norwegian ParkWest study.
Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2010
Alves Guido, Brønnick Kolbjørn, Aarsland Dag, Blennow Kaj, Zetterberg Henrik, Ballard Clive, Kurz Martin Wilhelm, Andreasson Ulf, Tysnes Ole-Bjørn, Larsen Jan Petter, Mulugeta Ezra
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) pathology is found in a considerable portion of patients with Parkinson's disease (PD), particularly those with early dementia (PDD). Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau proteins have been found in PDD, with intermediate changes for Aβ42 in non-demented PD. The authors investigated whether AD-related CSF protein levels are altered and relate to...
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