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Article

FcγR Genetic Variation and HIV-1 Vaccine Efficacy: Context And Considerations.

Frontiers in immunology - 1 Jan 2021

Lassaunière Ria, Tiemessen Caroline T

Abstract excerpt

Receptors for the crystallisable fragment (Fc) of immunoglobulin (Ig) G, Fcγ receptors (FcγRs), link the humoral and cellular arms of the immune response, providing a diverse armamentarium of antimicrobial effector functions. Findings from HIV-1 vaccine efficacy trials highlight the need for further study of Fc-FcR interactions in understanding what may constitute vaccine-induced protective immunity. These...

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Identifiers

PMID: 34975881
DOI: 10.3389/fimmu.2021.788203
PMCID: PMC8714752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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