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Article

Getting Access to Low-Complexity Domain Modifications.

Trends in biochemical sciences - 1 Nov 2016

Schüller Roland, Eick Dirk

Abstract excerpt

Low-complexity (LC) domains regulate the aggregation and phase transition of proteins in a modification-dependent manner. The study of LC domain modifications has now become feasible, as shown by genetic variants of the carboxy-terminal domain (CTD) of RNA Polymerase II (Pol II) that provide access to the type and position of modifications of a LC domain by mass spectrometry (MS).

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Identifiers

PMID: 27283512
DOI: 10.1016/j.tibs.2016.05.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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