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Article

Prospective longitudinal voxel-based morphometry study of major depressive disorder in young individuals at high familial risk.

Psychological medicine - 1 Aug 2016

Nickson T, Chan S W Y, Papmeyer M, Romaniuk L, Macdonald A, Stewart T, Kielty S, Lawrie S M, Hall J, Sussmann J E, McIntosh A M, Whalley H C

Abstract excerpt

BACKGROUND: Previous neuroimaging studies indicate abnormalities in cortico-limbic circuitry in mood disorder. Here we employ prospective longitudinal voxel-based morphometry to examine the trajectory of these abnormalities during early stages of illness development. METHOD: Unaffected individuals (16-25 years) at high and low familial risk of mood disorder underwent structural brain imaging on two occasions 2...

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Identifiers

PMID: 27282778
DOI: 10.1017/S0033291716000519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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