Article
Dissociable brain structural changes associated with predisposition, resilience, and disease expression in bipolar disorder.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Sept 2009
Kempton Matthew J, Haldane Morgan, Jogia Jigar, Grasby Paul M, Collier David, Frangou Sophia
Abstract excerpt
Genetic factors are important in the etiology of bipolar disorder (BD). However, first-degree relatives of BD patients are at risk for a number of psychiatric conditions, most commonly major depressive disorder (MDD), although the majority remain well. The purpose of the present study was to identify potential brain structural correlates for risk and resilience to mood disorders in patients with BD, type I (BD-I)...
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