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Article

Using the high-risk family design to identify biomarkers for major depression.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 1 Jan 2013

Talati Ardesheer, Weissman Myrna M, Hamilton Steven P

Abstract excerpt

The familial nature of major depressive disorder (MDD) is now well recognized. We followed children and grandchildren of probands with and without MDD to examine transmission of depression over generations, and to identify early vulnerability markers prior to the onset of disease. The study now i...

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Identifiers

PMID: 23440463
DOI: 10.1098/rstb.2012.0129
PMCID: PMC3638382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23440463-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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