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GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis

9 Jun 2016

Abstract excerpt

To identify genes and biologically relevant pathways associated with risk to develop multiple sclerosis (MS), the Genome-Wide Association Studies noise reduction method (GWAS-NR) was applied to MS genotyping data. Regions of association were defined based on the significance of linkage disequilibrium blocks. Candidate genes were cross-referenced based on a review of current literature, with attention to molecular...

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PMID: 27278126
DOI: 10.1038/gene.2016.23

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