Article
A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches.
Human genetics - 1 Nov 2015
Bashinskaya V V, Kulakova O G, Boyko A N, Favorov A V, Favorova O O
Abstract excerpt
Multiple sclerosis (MS) is a common complex neurodegenerative disease of the central nervous system. It develops with autoimmune inflammation and demyelination. Genome-wide association studies (GWASs) serve as a powerful tool for investigating the genetic architecture of MS and are generally used to identify the genetic factors of disease susceptibility, clinical phenotypes, and treatment response. This review...
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