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Article

The Caenorhabditis elegans T-box factor MLS-1 requires Groucho co-repressor interaction for uterine muscle specification.

PLoS genetics - 1 Aug 2011

Miller Raymond R, Okkema Peter G

Abstract excerpt

T-box proteins are conserved transcription factors that play crucial roles in development of all metazoans; and, in humans, mutations affecting T-box genes are associated with a variety of congenital diseases and cancers. Despite the importance of this transcription factor family, very little is known regarding how T-box factors regulate gene expression. The Caenorhabditis elegans genome contains 21 T-box genes,...

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Identifiers

PMID: 21852953
DOI: 10.1371/journal.pgen.1002210
PMCID: PMC3154951

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