Article
Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana.
PLoS genetics - 1 Jun 2016
Hale Christopher J, Potok Magdalena E, Lopez Jennifer, Do Truman, Liu Ao, Gallego-Bartolome Javier, Michaels Scott D, Jacobsen Steven E
Abstract excerpt
Eukaryotic genomes are regulated by epigenetic marks that act to modulate transcriptional control as well as to regulate DNA replication and repair. In Arabidopsis thaliana, mutation of the ATXR5 and ATXR6 histone methyltransferases causes reduction in histone H3 lysine 27 monomethylation, transcriptional upregulation of transposons, and a genome instability defect in which there is an accumulation of excess DNA...
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