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Article

The CaMKII/GluN2B Protein Interaction Maintains Synaptic Strength.

The Journal of biological chemistry - 29 Jul 2016

Barcomb Kelsey, Hell Johannes W, Benke Tim A, Bayer K Ulrich

Abstract excerpt

Learning, memory, and cognition are thought to require normal long-term potentiation (LTP) of synaptic strength, which in turn requires binding of the Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) to the NMDA-type glutamate receptor (NMDAR) subunit GluN2B. For LTP induction, many additional required players are known. Here we tested the hypothesis that CaMKII/GluN2B binding also mediates the more elusive...

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Identifiers

PMID: 27246855
DOI: 10.1074/jbc.M116.734822
PMCID: PMC4965558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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