Article
Host genetic variants influencing the clinical course of hepatitis B virus infection.
Journal of medical virology - 1 Mar 2016
Matsuura Kentaro, Isogawa Masanori, Tanaka Yasuhito
Abstract excerpt
The clinical course of hepatitis B virus (HBV) infection greatly differs in individuals. Various viral, host, and environmental factors influence the natural history of HBV infection. Recent genome-wide association studies identified several host genetic factors influencing the clinical course of HBV infection. Genetic variations in HLA class II loci were significantly associated with susceptibility to persistent...
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